Pemvidutide (ALT-801) is a GLP-1R/GCGR dual agonist that shows striking reductions in body weight, liver fat, and serum lipids. Pemvidutide can be used in non-alcoholic steatohepatitis (NASH) and obesity research.

Pemvidutide is a weight loss treatment delivered in the form of a pen that you use for weekly subcutaneous injections (under the skin’s fatty layer). It works by suppressing your appetite, allowing you to feel less hungry. As a result, you can gradually lose weight over time, especially as you make lifestyle adjustments.

The medication in Pemvidutide belongs to a class known as glucagon-like peptide-1 agonists. They work by replicating the function of GLP-1, a hormone your stomach releases whenever you eat. GLP-1 receptor agonists are often used to treat diabetes and obesity.

They’ve been studied and found to promote an average weight loss of nearly three kilograms, as well as reduce blood pressure and cholesterol.

Pemvidutide will start to work in your system from the first injection, but it’s usually weeks before you’ll start to notice your weight coming down. In a trial in Australia that looked at the effects of Pemvidutide in obese and overweight volunteers, patients were shown to lose weight rapidly and consistently over 12 weeks.

Losing weight relies on lifestyle and dietary changes, alongside using medication like Pemvidutide. Some people who use the injections might lose weight at a faster rate than others, but that doesn’t mean the injections aren’t working. You can speak to a clinician if you feel like Pemvidutide isn’t helping you lose weight at the rate you want it to.

GLP-1 receptor agonists are designed to be used in a very specific way. When you change your doses of Pemvidutide, you’ll be doing it under the supervision of a clinician who will be helping you lose weight in a safe, controlled way. This means there’s never any need to use more pemvidutide than you need.

You’ll only need to use your pen once a week. If you forget your injection at the usual time, you should be able to use your Pemvidutide pen as soon as you remember, provided it’s not too close to the time your next dose is due. If it’s less than 48 hours until your next injection, you can just skip the dose you missed.

If you take too much Pemvidutide, you should go to the hospital immediately and bring the box your medication arrived in with you. This will help hospital staff get you the help you need. Taking too much of this medication might cause nausea and other side effects that can make you feel ill.

You should never stop using Pemvidutide immediately without speaking to a medical expert first.